Protein Details: Voltage-gated sodium channel subunit beta-1

Function

Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain; heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits; such as SCN1A; SCN2A; SCN3A; SCN4A; SCN5A and SCN10A.

Sequence

PDB Structures

Ligand Binding